RNA Interference (RNAi)
RNAi has emerged as a powerful tool for therapeutic gene silencing....Its potential for therapy is indisputable, considering that one can use this mechanism to silence genes implicated in carcinogenesis and metastasis.
RNA interference (RNAi) is a natural mechanism used by the cell to regulate its molecular fate. RNAi can be compared to a system of switches on a circuit-board, which ultimately direct how information flows inside the cell. Specifically, in RNAi, short double-stranded RNA oligonucleotides inhibit the expression of genes with complementary nucleotide sequences, similar to the way a key and lock interact. RNAi has emerged as a powerful tool for therapeutic gene silencing because of its potency, modularity, broad applicability (virtually any gene can be silenced), and potential for exquisite specificity (single nucleotide). Its potential for therapy is indisputable, considering that one can use this mechanism to silence genes implicated in carcinogenesis and metastasis.
Transforming the diagnosis and treatment of cancer
TransCode Therapeutics, Inc., an RNAi Company, is focused on the discovery, development and commercialization of a pipeline of innovative diagnostics and therapeutics for the detection and treatment of cancer, with an initial focus on metastasis. TransCode’s vision is to be the leader in RNAi in oncology employing data-driven cancer diagnostics as well as optimized targeted treatment solutions for each individual cancer patient that results in a significant improvement in their outcome.
Using RNAi - Individualized Patient Approach
Conventional therapies aimed at treating primary cancer oftentimes are ineffective at treating metastatic cancer, resulting in poor outcomes in patients diagnosed with metastatic disease.
Improve Cancer Outcomes
Image-guided Delivery Platform
The staple of reducing mortality due to cancer has been early detection.
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