TRANSCODE THERAPEUTICS, INC.
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Pipeline

THERAPEUTIC PIPELINE
We have created a platform of drug candidates with the objective of improving patient outcomes. Our lead therapeutic candidate, TTX-MC138, is focused on treating metastatic cancer, which has been shown to be responsible for approximately 90% of all cancer deaths annually. We believe that TTX-MC138 has the potential to produce regression without recurrence in a range of cancers, including breast, pancreatic, ovarian and colon cancer, glioblastomas and others. Additionally, the Company’s other drug candidates, TTX-siPDL1, TTX-siLIN28b, TTX-RIGA, TTX-CRISPR and TTX-mRNA, focus on treating cancer using RNA technology made possible through its proprietary delivery platform.
​Currently TransCode is continuing research on a variety of both diagnostic and therapeutic approaches targeting biomarkers broadly prevalent across numerous tumor types. 
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CLINICAL PLAN

Establishing Proof of Concept

As a next step, the company intends to advance TTX-MC138 to the clinic to be evaluated in human subjects suffering from late stage cancer. TransCode has received written guidance from the FDA in response to our pre-IND submission for our proposed first-in-human study​​ and we are proceeding ahead under that guidance. Based on the results of this study, the exploratory IND will be withdrawn, and a full IND will be submitted to support a Phase I/II clinical trial intended to evaluate safety and dose/response and treatment of patients with metastatic cancer.  ​


The FDA has not evaluated or approved TTX-MC138 and it is currently not available for patient use.

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© TRANSCODE THERAPEUTICS, INC. 2022.​ ALL RIGHTS RESERVED.
  • Home
  • About
  • TTX Platform
  • Delivery Evidence
  • Pipeline
    • Drug Pipeline
    • TTX-MC138
    • TTX-siPDL1
    • TTX-siLIN28b
    • TCDx
  • Contact
  • Investor Relations